Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.
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Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES (00:29:29)
Christopher Mims and Tim Higgins of the Wall Street Journal sit down with a16z General Partner Martin Casado on WSJ’s Bold Names to ask whether the AI spending boom is a bubble waiting to burst. Marti...
Martin Casado on the Demand Forces Behind AI (00:27:59)
In this feed drop from The Six Five Pod, a16z General Partner Martin Casado discusses how AI is changing infrastructure, software, and enterprise purchasing. He explains why current constraints are dr...
How Mintlify Is Rebuilding Documentation for Coding Agents (00:44:48)
Mintlify is a documentation platform built by cofounders Han Wang and Hahnbee Lee to help teams create and maintain developer docs. In this episode, Andreessen Horowitz general partners Jennifer Li an...
Inferact: Building the Infrastructure That Runs Modern AI (00:43:37)
Inferact is a new AI infrastructure company founded by the creators and core maintainers of vLLM. Its mission is to build a universal, open-source inference layer that makes large AI models faster, ch...
How Should AI Be Regulated? Use vs. Development (00:46:45)
To Regulate AI Effectively, Focus on How It’s UsedA conversation with Martin Casado on learning from past computing platform shifts, understanding marginal risk in AI, and why open source matters for ...
Michael Truell: How Cursor Builds at the Speed of AI (00:27:30)
When four MIT grads decided to build a code editor while everyone else was building AI agents, they created the fastest-growing developer tool ever built. Cursor CEO Michael Truell joins a16z’s Martin...
Dylan Patel on the AI Chip Race - NVIDIA, Intel & the US Government (01:40:00)
Nvidia’s $5 billion investment in Intel is one of the biggest surprises in semiconductors in years. Two longtime rivals are now teaming up, and the ripple effects could reshape AI, cloud, and the glob...
Feed Drop from The Generalist: Why a16z's Martin Casado believes the AI boom still has years to run (01:21:52)
This episode is a special replay from The Generalist Podcast, featuring a conversation with a16z General Partner Martin Casado. Martin has lived through multiple tech waves as a founder, researcher, a...
Fei-Fei Li: World Models and the Multiverse (00:22:56)
What if the next leap in artificial intelligence isn’t about better language—but better understanding of space?In this episode, a16z General Partner Erik Torenberg moderates a conversation with Fei-Fe...
Building the “See Something, Say Something” AI for Every Camera (00:39:25)
a16z's Martin Casado sits down with Shikhar Shrestha, CEO and cofounder of Ambient, the company bringing agentic AI to physical security.Shikhar shares how a traumatic armed robbery at age 12—and a se...
The AI That Found A Bug In The World’s Most Audited Code (00:39:12)
Matt Knight spent five years as OpenAI’s CISO. Now he runs what colleagues call “the most interesting job at the company”: leading Aardvark, an AI agent that finds security vulnerabilities the way a h...
The Death of Data Gatekeeping: AI Makes Everyone An Analyst | Hex Cofounder (01:22:53)
Most companies still rely on dashboards to understand their data, even though AI now offers new ways to ask questions and explore information. Barry McCardel, CEO of Hex and former engineer at Palanti...
Why Social Engineering Now Works on Machines (00:25:14)
Ian Webster built PromptFoo after watching 200 million Discord users systematically dismantle his AI agent—now Fortune 10 companies pay him to break theirs before customers do. The "lethal trifecta" s...
“Anyone Can Code Now” - Netlify CEO Talks AI Agents (00:57:59)
Netlify's CEO, Matt Biilmann, reveals a seismic shift nobody saw coming: 16,000 daily signups—five times last year's rate—and 96% aren't coming from AI coding tools. They're everyday people accidental...
From Code Search to AI Agents: Inside Sourcegraph's Transformation with CTO Beyang Liu (00:46:35)
Sourcegraph's CTO just revealed why 90% of his code now comes from agents—and why the Chinese models powering America's AI future should terrify Washington. While Silicon Valley obsesses over AGI apoc...
Ryo Lu (Cursor): AI Turns Designers to Developers (00:52:01)
Ryo Lu spent years watching his designs die in meetings. Then he discovered the tool that lets designers ship code at the speed of thought: Cursor, the company where Ryo is now Head of Design. In this...
How Foundation Models Evolved: A PhD Journey Through AI's Breakthrough Era (00:57:06)
The Stanford PhD who built DSPy thought he was just creating better prompts—until he realized he'd accidentally invented a new paradigm that makes LLMs actually programmable. While everyone obsesses o...
TruffleHog Creator: You Can’t Have AI Agents Without Secrets (00:28:37)
If you can’t robustly protect your secrets, you can’t have reliable AI agents.In this episode, Truffle Security cofounder and CEO Dylan Ayrey joins a16z partner Joel de la Garza to discuss the emergen...
Tigris Data CEO on Building Your Own Datacenters (00:38:43)
In this episode, a16z General Partner Martin Casado sits down with Ovais Tariq, Cofounder and CEO of Tigris Data, to discuss why independent storage is so hard, what operating your own datacenters is ...
Pylon: Reimagining B2B Customer Support (00:47:31)
Customer support platforms lacked adequate solutions for B2B companies - until Pylon entered the scene.We sat down with Pylon cofounders Marty Kausas, Advith Chelikani, and Robert Eng to discuss why t...
Keycard: 2026 is the Year of Agents (00:32:41)
In 2025, we saw the first glimpses of true AI agents. In 2026, every company will be rushing to get them into production, and they’ll need companies like Keycard to manage fleets of agents.In this con...
The Trillion Dollar AI Software Development Stack (00:38:06)
AI coding has emerged as a major market for AI: one that’s already rewriting how software gets built.a16z Infra Partners Yoko Li and Guido Appenzeller break down how “agents with environments” are cha...
Material Security CEO: How To Find Your Ideal Customer (00:34:26)
What if the hardest part of building a company isn’t the product, but knowing exactly who it’s for?In this episode, a16z General Partner Martin Casado sits down with Abhishek Agrawal, Cofounder and CE...
When Deepfakes Steal $30M: The New Edge of Cybercrime (00:22:11)
AI is transforming both sides of the cybersecurity cat-and-mouse game. Attackers are using LLMs to scale impersonation, phishing, and even deepfake fraud—while defenders are racing to automate detecti...
How AI Will Change Photography Forever (00:51:41)
What if you could retake your favorite memories years after they happened, fixing the lighting, catching the smile, or even opening your eyes?In this conversation, a16z General Partner Martin Casado a...
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