Each episode of AJP Audio brings you an in-depth look at one of the articles featured in that month's issue of The American Journal of Psychiatry, the official journal of the American Psychiatric Association. Wide-ranging interviews with article authors cover the background, rationale, main findings, and future implications of the research.
This podcast is subject to the Terms of Use at ww.psychiatry.org. The views and opinions expressed in this podcast are those of the individual speakers only and do not necessarily represent the views of the American Psychiatric Association, its officers, trustees, or members. The content of this podcast is provided for general informational purposes only and is not intended as, and shall not be understood or construed as, medical or any other type of professional advice nor does it represent any statement of the standard of care. We strongly recommend that any listener follow the advice of physicians directly involved in their care and contact their local emergency response number for any medical emergency. The information within this podcast is provided as-is and is not guaranteed to be correct, complete, or accurate.
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February 2026: Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial (00:29:58)
Dr. Ian Kelleher (University of Edinburgh, Scotland) joins AJP Audio to discuss an emulated target trial looking at the prophylactic qualities of doxycycline, an antibiotic, in an adolescent populatio...
Special Episode: 2025 Articles of Import and Impact (00:33:12)
This special episode of AJP Audio brings together the editors of the American Journal Psychiatry and the AJP Residents' Journal to discuss important and impactful articles published in 2025. 00:39 ...
January 2026: Reduced Threat-Related Neural Efficiency: A Possible Biomarker for Pediatric Anxiety Disorders (00:26:13)
Dr. Julia Linke (University of Mainz, Germany) joins AJP Audio to discuss the use of neural efficiency, a measure of brain activity, as a potential biomarker in the treatment of children with anxiety ...
December 2025: Adjunctive Lumateperone in Patients With Major Depressive Disorder: Results From a Randomized, Double-Blind, Phase 3 Trial (00:22:12)
Dr. Suresh Durgam (Intra-Cellular Therapies, a Johnson & Johnson Company, Bedminster, NJ) joins AJP Audio to discuss a phase 3 randomized controlled trial looking at the use of the antipsychotic medic...
November 2025: Contingency Management for Stimulant Use Disorder and Association With Mortality: A Cohort Study (00:27:14)
Dr. Lara Coughlin (University of Michigan, Ann Arbor) joins AJP Audio to discuss a study looking the impact of contingency management on all cause mortality in patients with stimulant use disorder. Af...
October 2025: Differential Effects of Ovarian Steroids in Women With and Without Premenstrual Dysphoric Disorder: A Replication and Extension of Findings (00:26:47)
Dr. Shau-Ming Wei (National Institute of Mental Health, Bethesda, MD) joins AJP Audio to discuss a replication study looking at impact of hormone addback to a hormone suppression regimen for the treat...
September 2025: Neighborhood Social Vulnerability and Racial Disparities in Schizophrenia Spectrum Disorder Prevalence (00:39:52)
Dr. Deidre Anglin (City College, CUNY, New York) joins AJP Audio to discuss the disparate impact of schizophrenia spectrum disorder diagnosis on racial and ethnic minorities in the United States based...
August 2025: Telehealth Prescribing of Stimulants for ADHD and Associated Risk for Later Stimulant and Substance Use Disorders (00:33:44)
Dr. Vinod Rao (Massachusetts General Hospital, Boston) join AJP Audio to discuss predicting the relative risk of patients with an ADHD diagnosis developing a later stimulant or substance use disorder ...
July 2025: National Trends in Suicidal Thoughts and Suicide Attempts Among High School Students in the United States (00:24:58)
Dr. Tanner Bommersbach (University of Wisconsin School of Medicine and Public Health) and Dr. Greg Rhee (University of Connecticut and Yale University School of Medicine) join AJP Audio to discuss est...
June 2025: Stratifying Risk for Postpartum Depression at Time of Hospital Discharge (00:32:41)
Dr. Roy Perlis (Mass General Bringham, Boston) joins AJP Audio to discuss a machine learning model to examine electronic health records in individuals who had recently given birth designed to detect t...
May 2025: Randomized Controlled Trial of "Bounce Back Now," a Mobile App to Reduce Post-Disaster Symptoms of Posttraumatic Stress, Depressed Mood, and Sleep Disturbance (00:36:20)
Dr. Kenneth Ruggiero (Medical University of South Carolina, Charleston) joins AJP Audio to discuss the the effectiveness of an app-based intervention at reducing the symptoms of sleeplessness and p...
April 2025: Anticholinergic Burden and Cognitive Function in Psychosis: A Systematic Review and Meta-Analysis (00:23:11)
Dr. Valentina Mancini (Oxford University) joins AJP Audio to discuss the impact of anticholinergic burden on cognition in patients with schizophrenia. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin pu...
March 2025: The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials (00:32:05)
Dr. William Horan (Bristol Myers Squibb) joins AJP Audio to discuss a newly approved, novel treatment for schizophrenia spectrum disorder, which has potential impacts for cognition in patients. After...
February 2025: Real-Time Assessment of Alcohol Reward, Stimulation, and Negative Affect in Individuals With and Without Alcohol Use Disorder and Depressive Disorders (00:44:45)
Dr. Andrea King (University of Chicago Medicine) joins AJP Audio to discuss a novel, real time assessment of the reward, stimulation, and negative affect of alcohol use in people with alcohol use diso...
January 2025: Special Issue on Psychedelics (00:19:28)
Dr. Charles Nemeroff (University of Texas at Austin) joins AJP Editor-in-Chief Dr. Ned Kalin to discuss the January issue of the American Journal of Psychiatry. Dr. Nemeroff is a guest editor of the s...
December 2024: Discrimination Exposure, Neural Reactivity to Stress, and Psychological Distress (00:29:50)
Devon Grey and David Knight (University of Alabama, Birmingham) join AJP Audio to discuss how exposure to discrimination impacts neural reactivity to stress and psychological distress in adolescents. ...
November 2024: Disparities in Treatment for Alcohol Use Disorder Among All of Us Participants (00:27:36)
Dr. Phuc Le (Cleveland Clinic, Case Western Reserve University, Cleveland) joins AJP Audio to discuss racial, ethnic, and sociodemographic disparities in treatment in alcohol use disorder among partic...
October 2024: Real-World Effectiveness of Menopausal Hormone Therapy in Preventing Relapse in Women With Schizophrenia or Schizoaffective Disorder (00:36:01)
Dr. Bodyl Brand (Oxford University, UK) joins AJP Audio to discuss the effectiveness of menopausal hormone therapy in preventing psychosis relapse in women with schizophrenia and schizoaffective disor...
September 2024: Peer Social Genetic Effects and the Etiology of Substance Use Disorders, Major Depression, and Anxiety Disorder in a Swedish National Sample (00:30:18)
Dr. Jessica Salvatore (Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey) joins AJP Audio to discuss peer social genetic effects and their impact on alcohol and substance use, anxi...
August 2024: Sexual Identity Continuity and Change in a U.S. National Probability Sample of Sexual Minority Adults: Associations With Mental Health and Problematic Substance Use (00:29:32)
Dr. Evan Krueger (Tulane University School of Social Work) joins AJP Audio to discuss the impact of sexual identity change and continuity on the mental health and substance use of adults who identify ...
July 2024: Association of Occupational Dysfunction and Hospital Admissions With Different Polygenic Profiles in Bipolar Disorder (00:31:20)
Dr. Lina Jonsson (Sahlgrenska Academy at University of Gothenburg, Sweden) joins AJP Audio to discuss the association of occupational dysfunction and hospital admissions with polygenic profiles in pat...
June 2024: Long-Term Course of Remission and Recovery in Psychotic Disorders (00:29:23)
Ms. Sara Tramazzo (Stony Brook University) joins AJP Audio to discuss the long-term outlook for patients with schizophrenia spectrum disorders and other psychotic disorders over the course of 25 years...
May 2024: Predictors of Substance Use Initiation by Early Adolescence (00:36:45)
Dr. ReJoyce Green (Medical University of South Carolina, Charleston, SC) joins AJP Audio to discuss predictors of substance use initiation in a large cohort of early adolescents. Afterwards, AJP Edito...
April 2024: Neural Responses to Intranasal Oxytocin in Youths With Severe Irritability (00:27:39)
Dr. Soonjo Hwang (University of Nebraska Medical Center) joins AJP Audio to discuss the response to intranasally-administered oxytocin in youths with severe irritability. 00:56 Hwang interview 02...
March 2024: Intergenerational Effects of the Fast Track Intervention on Next-Generation Child Outcomes: A Preregistered Randomized Clinical Trial (00:27:55)
Dr. Drew Rothenberg (Duke University, Durham, NC) joins AJP Audio to discuss the long term, intergenerational impacts of the Fast Track program, and whether the mental health intervention lead to last...