Welcome to Basics to Brilliance, the podcast created to supplement & bolster your knowledge of Haematology.Featuring a two way, non-didactic conversational-style Q&A between the SpR and SHO, this podcast will be your pocket companion no matter where you are.We aim to cover: - Malignant and non-malignant topics- Science/lab detail- UK guidelines, hallmark trials and how these translate into clinical practice- Future research directions- The whole syllabus for FRCPath part 1All readily accessible and completely free of charge!For every budding haematologist out there, we hope this podcast aids you in your endeavours and fills you with interest and excitement for the brilliant world of Haematology. Warmest Regards,Dr. EverdenDr. FaseyDr. JafriDisclaimer: This podcast is intended as a revision aid and should not be used for the medical management of patients. Guidelines in the initial episodes span 2023/2024. We aim to update our content in accordance with the most recent available guidelines when possible. This podcast is CPD accredited by the Royal College of Pathologists UK
📻 Siste episoder av Basics to Brilliance: Haematology Podcast
Her er de nyeste episodene tilgjengelige via RSS-feeden:
Laster episoder...
📱 Slik abonnerer du på Basics to Brilliance: Haematology Podcast
Feedback 00:52 Intro and chuckles 01:40 Case study: 75M, left calf swelling, put on DOAC, 24 hrs later haematoma and deep bleed on CT 06:00 General information Elderly (>65), Mortality 8-40%Common pre...
Haemophilia A in Pregnancy (00:50:16)
Feedback 00:52 Intro - very important topic 02:00 Case Study: Haem/Obstetrics clinic, Family Hx Severe Haemophilia A, 12wks pregnant 04:15 Clotting changes in pregnancy Increased: FVII, FVIII, FX, VWF...
Haemophilia A: Inhibitors (00:53:59)
Feedback 00:52 Intro 02:10 Definition Common: Alloantibody neutralizes FVIIIRare: causes increased clearance of FVIII1/3 of Severe Haemophilia A patientsMedian time 10-15 emergency dosesRF: Mutation t...
Haemophilia A: Management Basics (01:24:40)
Feedback 00:52 Intro 02:35 Structure of Haemophilia A care 05:10 Key aspects of management (On-demand vs prophylaxis) 07:00 Prophylaxis: reduce death rates from ICH and reducing joint bleeds - Primary...
Feedback 00:52 Intro 02:00 What is Haemophilia A? 03:00 Factor VIII, Pathogenesis of Haemophilia A 07:10 Structure of Factor VIII (exam pearl) 300kDHeavy (A1 A2, B) + Light Chain (A3, C1, C2) bound by...
Factor XIII (13), Fibrinolysis & Thrombolysis (00:46:21)
Feedback 01:45 Case: Neonate with repeated umblical bleeding. IC haemorrhage. Normal Factors (so far), Normal VW screen, Normal FBC and normal film. 05:35 Factor XIII (13): function and presentations...
Inhibitors in Haemostasis (01:03:02)
Feedback 00:52 Intro: definition and prompts 04:25 Intro to Case 1: Haemophilia B, 3rd dose of BeneFix Anaphylaxis 06:03 Intro to Case 2: Severe Haemophilia A, joint bleed, non-responsive to emergenc...
Heparin & the Anti-Xa Assay (00:59:29)
Feedback 00:52 Intro (shoutuout to the BSH anticoagulant monitoring guidelines) 02:15 Practical relevance of testing and monitoring anticoagulants 07:30 Heparin: The Basics 09:00 Unfractionated Hepa...
Thrombin Time & Fibrinogen Assays (00:38:08)
Feedback 00:54 Intro and table of contents 1:48 Case 1: pre-op, prolonged PT and ++ prolonged APTT…thrombin time done 03:44 Case 2: post-op, normal PT and prolonged APTT…thrombin time done 04:46 Throm...
Mixing Studies & Factor Assays (00:51:35)
Feedback 0:52 Intro and table of contents 2:36 CASE 1- Infection, due surgery and a prolonged APTT ft. a refresher on APTT prolongation 08:00 Mixing studies- definition and uses ft. Hari’s exam nugge...
Mantle Cell Lymphoma (01:25:06)
Feedback 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK. Medical professionals and clinical scientists holding career-grade...
Practical Haemostasis of the Clotting Screen (00:34:27)
Feedback 00:00 Intro 04:25 Automated Methods of Measuring a Clot 05:50 Scenario 1 & Pre-Analytical Variables 11:50 HIL Index & Patient Factors 15:55 Blood Tube Basics 21:10 Nitty Gritties- What Happen...
The Clotting Screen: Back to Basics (00:45:19)
Feedback 0:00 Intro 2:45 What is Haemostasis? 3:55 Stages of Haemostasis (summary) 4:45 Primary Haemostasis 8:35 Secondary Haemostasis 11:10 The Clotting Cascade 12:20 Common + Extrinsic Pathway 13:5...
Essential Thrombocythemia (ET) (01:11:45)
Feedback 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK. Medical professionals and clinical scientists holding career-grade...
Immune Thrombocytopenia (ITP) (01:18:24)
Feedback 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK. Medical professionals and clinical scientists holding career-grade...
Heparin Induced Thrombocytopenia (HIT) (01:00:26)
Feedback 'Basics to Brilliance: Haematology Podcast' has been accredited for CPD credit by the Royal College of Pathologists UK. Medical professionals and clinical scientists holding career-grade...
Polycythemia Rubra Vera (PRV) (01:12:33)
Feedback Polycythaemia- red cell # Erythrocytosis – in red cell mass Absolute Erythrocytosis - M: Hct >0.60 or >0.52 + RCM >25% of mean - F: Hct >0.56 or >0.48 + RCM >25% of mean Apparent Erythrocyt...
Secondary CNS Lymphoma (00:37:30)
Feedback - Synchronous CNS and systemic lymphoma at initial presentation (treatment-naïve; TN-SCNSL) - CNS relapse without recurrent systemic lymphoma (relapsed isolated CNS lymphoma; RI-...
Primary CNS Lymphoma (01:09:06)
Feedback CNS Lymphomas 1% of all NHL 3% of all Brain tumours Most common subtype (90%) is DLBCL Clinical division: 1. 1* CNS lymphoma, 2. 2* CNS lymphoma - TN-SCNSL - RI-SCNSL - RC-SCNSL 3. Immun...
Chronic Monomyelocytic Leukemia (CMML) (00:41:56)
Feedback Chronic MyeloMonocytic Leukemia (not CML) Persistently high monocyte count- 3 months Most frequent MDS/Myeloproliferative neoplasms – a cross between the two Median age 72 Median survival 2...
Chronic Lymphocytic Leukemia (CLL) (01:18:33)
Feedback Chronic Lymphocytic Leukemia (CLL)- Chronic Relapsing Remitting Most common leukemia in adults Incurable but treatable *Remember Supportive Care* Median age of 72 M > F 80% incidental SLL: l...
