Beyond the Endpoint
VitenskapThe Duke Clinical Research Institute is drawing on gold-standard research and real-world evidence to bring you Beyond the Endpoint, a podcast that is demystifying clinical research and healthcare through conversations with renowned clinicians and scientists.
Siste episoder av Beyond the Endpoint podcast
- Beyond the Headlines: Funding Research, Vaccines, Sleep Health, and AI in Healthcare (00:26:43)
The "Beyond the Headlines" series returns with summer healthcare and research news. Hosts Manesh Patel and Emily O'Brien discuss misconceptions about research funding, a Danish study on vaccine safety, the potential impacts of poor sleep, and how AI tools are transforming medical practice and training. Tags: #medicalnews #healthnews #research #clinicalresearch
- Understanding Autism: Insights from Research and Practice (00:26:02)
Ushering in the second season of Beyond the Endpoint, Lauren Franz, MBChB, MPH, interim director of the Duke Center for Autism and Brain Development, joins Manesh Patel and Emily O'Brien for an in-depth conversation about autism research, care, and community. Franz explains what autism is as a neurodevelopmental spectrum condition and how our understanding of it has evolved significantly over the last decade. The discussion examines the intricate interplay between genetic and environmental factors that may contribute to the development of autism, and explores current intervention approaches. The hosts and guest also discuss the groundbreaking research at Duke University that employs artificial intelligence to analyze medical records for earlier detection of autism. This approach could help shorten the time between when autism can be diagnosed and when it is typically identified. Throughout the episode, Franz stresses the importance of involving the autism community in research and decision-making processes.
- Playing to Advance Care: A Championship Mindset in Clinical Research (00:34:35)
What do championship sports teams and successful research institutions have in common? In the season finale of Beyond the Endpoint, Dr. Adrian Hernandez joins hosts Manesh Patel and Emily O’Brien to break down what clinical research institutions can learn from their counterparts on the court. From basketball dynasties to resilient mindsets, Dr. Hernandez offers a powerful playbook on building strong research systems, prioritizing patients, and why sharing “negative” results matters. Don’t miss the wrap-up to Season 1! 🔗 Access resources related to this episode https://dcri.org/blog/ep-10-playing-advance-care-championship-mindset-clinical-research
- Beyond the Headlines: Protein myths. Anti-aging hype. Autism research. A new diabetes drug? (00:24:53)
In this new episode of the Beyond the Endpoint series, “Beyond the Headlines,” hosts Emily O’Brien and Manesh Patel break down what’s you should know about these trending medical topics. From hype to headlines—get clinical insight that goes deeper. Access resources related to this episode https://dcri.org/blog/ep-9-beyond-headlines 187880
- Stepping Up: From Curiosity to Confidence — What to Know Before You Join a Trial (00:24:41)
Why do people volunteer for clinical trials — and what should they know before doing so? In this episode of Beyond The Endpoint, we explore common questions, reasons, and myths about clinical trial participation. Hosts Manesh Patel and Emily O’Brien talk with guest Krista Camuglia, a Research Practice Manager with the Duke Heart Center Clinical Research Unit, who brings unique insights thanks to her work on the frontlines of research coordination. 🎙️ Listen to "Part 1: Why Participate in Clinical Research?" https://dcri.org/blog/ep-7-stepping-why-participate-clinical-research
- Stepping Up: Why Participate in Clinical Research? (00:32:13)
In this episode, cancer survivor Katie Ortman-Doble opens up about her journey through clinical research and why she chose to participate. Hosts Emily O’Brien and Manesh Patel, joined by Jenny Cook, talk about the life-saving potential of clinical trials and the real impact they have on patients and science. Hear Katie’s inspiring story and the reasons behind her decision to join a trial. 🔗 Access resources related to this episode https://dcri.org/blog/ep-7-stepping-why-participate-clinical-research
- Bridging Science and Policy: A Conversation with Dr. Robert Califf (00:31:07)
In this episode of Beyond the Endpoint, former FDA commissioner Dr. Robert Califf joins hosts Manesh Patel and Emily O’Brien to discuss critical challenges shaping the future of patient care. From misinformation to regulatory science to the financialization of healthcare, Dr. Califf has unique insight into the evolving healthcare landscape and the role of data in improving patient outcomes. 🔗 Access resources related to this episode https://dcri.org/blog/ep-6-bridging-science-and-policy-conversation-dr-robert-califf
- Beyond the Headlines: What’s trending in medical news? (00:25:52)
Ozempic curbing alcohol cravings, ADHD linked to shorter life expectancy, and an NBA rising star diagnosed with DVT—what does the science actually say? In this first episode of Beyond the Headlines, a new Beyond the Endpoint series, hosts Emily O’Brien and Manesh Patel break down the research behind these trending stories. Access resources related to this episode https://dcri.org/blog/ep-5-beyond-headlines
- Wearables in Clinical Research: Data, Trends, and Challenges (00:35:31)
Smartwatches, fitness trackers, and health data—how are wearables reshaping clinical research? In this episode, Dr. Marat Fudim joins us for an insightful discussion on how wearable technology is shaping the way we monitor health and conduct research. Topics include: • Are wearables improving patient care or just tracking steps? • How do researchers use wearable data in clinical trials? •What are the biggest challenges in integrating this tech? 🎙️ Listen now and explore the possibilities of wearable health tech! 🔗 Access resources related to this episode https://dcri.org/blog/ep-4-wearables-clinical-research-data-trends-and-challenges
- The Intersection of Politics and Medicine: Impacts on Clinical Practice (00:32:37)
In this episode of Beyond the Endpoint, Emily O’Brien and Manesh Patel sit down with Leslie Curtis, former senior FDA policy advisor, to explore the FDA’s role in balancing science, public health, and regulation, along with how political transitions influence clinical research, healthcare funding, and the approval process for new treatments. 🔗 Access resources related to this episode https://dcri.org/blog/ep-3-intersection-politics-and-medicine-impacts-clinical-practice
- Bending the Curve on Hypertension (00:34:18)
Reducing hypertension risk isn’t just about cutting salt. This week on Beyond The Endpoint, Emily O’Brien, Manesh Patel, and Jenny Cook talk with Dr. Dhruv Kazi about the complex public health battle against hypertension. From interventions to strategies for patient and physician adherence, this episode covers scalable solutions to change the future of hypertension. 🔗 Access resources related to this episode https://dcri.org/blog/ep-2-bending-curve-rewriting-future-hypertension
- Caring Through Loss: The Role of Grief in Clinical Settings (00:34:56)
In this episode of "Beyond the Endpoint," hosts Emily O'Brien and Manesh Patel are joined by guest host Jenny Cook to discuss grief among healthcare providers with Tony Galanos, a researcher and physician at the Duke University School of Medicine. Galanos — "Dr. G" as he's called around Duke — shares insights from his 12-year program helping other clinicians to address and process the grief that can be an inevitable part of their work. He highlights the emotional toll that healthcare work can take and the importance of acknowledging and processing grief. The episode explores the concept of the "hidden curriculum" in medical training, the practice of "the pause" after intense resuscitation efforts, and also dives into how everyone can better manage their own grief after losing a loved one. 🔗 Access resources related to this episode https://dcri.org/blog/ep-1-caring-through-loss-role-grief-clinical-settings
- Inviting Our Colleagues To Participate In DCRI On Record (00:04:58)
Inviting Our Colleagues To Participate In DCRI On Record by Duke Clinical Research Institute
- John Shepherd And Michele Nolen (00:03:44)
John Shepherd And Michele Nolen by Duke Clinical Research Institute
- Assessing Results of Open-label, Comparative Effectiveness Trials for Cardio-metabolic Drugs (00:17:03)
Assessing Results of Open-label, Comparative Effectiveness Trials for Cardio-metabolic Drugs by Duke Clinical Research Institute
- Duke IBD Podcast Series: IBD and Nutrition (00:14:55)
Duke IBD Podcast Series: IBD and Nutrition by Duke Clinical Research Institute
- IBD Podcast with Dr. Jane Onken (00:23:44)
IBD Podcast with Dr. Jane Onken by Duke Clinical Research Institute
- Patient Perspective Nutrition And Diet In Perioperative Recovery (00:14:59)
Patient Perspective Nutrition And Diet In Perioperative Recovery by Duke Clinical Research Institute
- Nutrition In ERAS: " A Call For Clinical Trials" (00:20:55)
Nutrition In ERAS: " A Call For Clinical Trials" by Duke Clinical Research Institute
- Data, Innovation & Guidelines in Gastroenterology – Deborah Fisher, MD (00:10:39)
Data, Innovation & Guidelines in Gastroenterology – Deborah Fisher, MD by Duke Clinical Research Institute
- Sunil Rao at TCT 2018: Meeting Highlights and the #RadialFirst Journey (00:07:22)
Sunil Rao at TCT 2018: Meeting Highlights and the #RadialFirst Journey by Duke Clinical Research Institute
- Renato Lopes at TCT 2018: SECURE-PCI and Timing for Statin Dosing (00:10:00)
Renato Lopes at TCT 2018: SECURE-PCI and Timing for Statin Dosing by Duke Clinical Research Institute
- Jennifer Rymer at TCT 2018: Aborted TAVR Procedures and Same-Day Discharge for PCI (00:10:22)
Jennifer Rymer at TCT 2018: Aborted TAVR Procedures and Same-Day Discharge for PCI by Duke Clinical Research Institute
- Nutrition in Surgery – The Clinician’s Perspective (00:27:01)
Nutrition in Surgery – The Clinician’s Perspective by Duke Clinical Research Institute
- The Role of the Dietician in Perioperative Nutrition Screening and Care (00:20:46)
The Role of the Dietician in Perioperative Nutrition Screening and Care by Duke Clinical Research Institute